All of Dr. Lis' publications listed on PubMed.

For selected papers by technique, see our Research Interests pages.

Selected Reviews:

• Lis, J. T. (2007) "Imaging Drosophila gene activation and polymerase pausing in vivo." Nature, 450(7167):198-202. (PubMed)
  
• Saunders, A., Core, L. J. and Lis, J. T. (2006) "Breaking Barriers to Transcription Elongation." Nature Reviews Molecular Cell Biology, 7: 557-567. (PubMed)
• Lis, J. (1998) "Promoter-Associated Pausing in Promoter Architecture and Post-Initiation Transcriptional Regulation." Cold Spring Harbor Symposium on Quantitative Biology. Volume LXIII. 347-56. (Article: PDF)

Here are some our images that have been featured on the covers of the publishing journals.  Click on the journal cover for the PubMed listing of the paper.

This page provides a series of resources which Lis Lab provides online, usually in conjunction with recent publications. Many of these resources are in PDF format and need to be downloaded and viewed using Adobe Acrobat Reader.

Full Text and Abstract (via ScienceMag.org) for Core, L.J. and Lis, J.T. (2008) "Transcription regulation through promoter-proximal pausing of RNA polymerase II." Science 319(5871):1791-2. (PubMed)

Supplemental data for Boehm et al. (2003) "Transcription factor and polymerase recruitment, modification, and movement on dhsp70 in vivo in the minutes following heat shock." Mol Cell Biol. 21:7628-37. (PubMed)

Full-size versions of the original images in Park et al. (2001) "Mediator, not holoenzyme, is directly recruited to the heat shock promoter by HSF upon heat shock." Mol Cell. 8(1):9-19. (PubMed). This file allows for more clear viewing of the figures than allowed for in the printed publication.

Full-size versions of the original images in Andrulis et al. (2000) "High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation." Genes Dev. 14(20):2635-49. (PubMed) This file allows for more clear viewing of the figures than allowed for in the printed publication.

Full-size versions of the original images in Lis et al. (2000) "P-TEFb kinase recruitment and function at heat shock loci." Genes Dev. 14(7):792-803. (PubMed) This file allows for more clear viewing of the figures than allowed for in the printed publication.

Supplemental text and figures for Lee et al. (1999) "Different upstream transcriptional activators have distinct coactivator requirements." Genes Dev. 13(22):2934-9. (PubMed)

Directions on the construction of the lambda phage library described in Lin and Lis (1999) "Glycogen synthase phosphatase interacts with heat shock factor to activate CUP1 gene transcription in Saccharomyces cerevisiae." Mol Cell Biol. 19(5):3237-45. (PubMed)

Article: Lis, J. "Promoter-Associated Pausing in Promoter Architecture and Post-Initiation Transcriptional Regulation." Cold Spring Harbor Symposium on Quantitative Biology. Volume LXIII. 1998. 347-56.