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Alani Lab in PLOS Biology

Apr 28, 2017
Alani Lab, The mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans Read more

Erich Schwarz featured in February 2017 Nature Methods

Feb 9, 2017
The GAL4 gene expression system has been a powerful tool for two-part control of fruit fly (Drosophila) genes for over two decades; but, until now, GAL4 has not worked in the model nematode Caenorhabditis elegans. Wang, Liu, and others have developed standardized driver and effector lines that use GAL4 from a cryophilic yeast species, Saccharomyces kudriavzevii. Unlike its more famous relative. S. cerevisiaeS. kudriavzevii grows well at temperatures close to 20 deg. C., the preferred growth temperature for C. elegans. Temperature-optimized GAL4 shows robust activity in C. elegans and should enable many new experiments in it. These findings have been published in the February 2017 issue of Nature Methods (http://dx.doi.org/10.1038/nmeth.4109), with a cover illustration representing C. elegans artistically by Voronoi tessellation. Erich Schwarz, research scientist in nematode genomics at MBG, was the Cornell member of this collaboration.
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MBG Postdoc Sri Raj on Forbes Magazine 30 under 30 list

Jan 6, 2017
Raj has been doing medical research since she was 14 years old. Now as a postdoc at Cornell, she works as a population geneticist focused on how evolutionary adaptations have elevated or lowered different groups' susceptibility to chronic disease. She's researched everything from hypertension in African patients to adaptation to cold among native Siberians. Read more

Human DNA influences gut bacteria

May 11, 2016
A Cornell-led study published May 11 in the journal Cell Host Microbe provides the strongest evidence yet that human DNA influences the type and number of bacteria that reside in each person’s gut. Read more

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